Search Results - timothy+mckinsey

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Heart Regeneration by Conversion of Non-myocytes into Functional Cardiomyocytes

se; } .TableNormal { telerik-style-type: table;telerik-style-name: TableNormal;border-collapse: collapse; } Low Regenerative Capability of Cardiomyocytes Heart failure affects about 8 million Americans of all ages every year. It considerably reduces quality of life with only a 50% five-year survival rate. Recent therapeutic approaches (drug development,...

Published: 9/27/2023 | Inventor(s): Kunhua Song, Yuanbiao Zhao, Pilar Londono, Timothy McKinsey

Disease Areas Regenerative Medicine

Category(s): Therapeutics

Treatment of Metabolic Syndrome and Obesity with HDAC11 Inhibitors

Researchers at the University of Colorado have found that histone deacetylase 11 (HDAC11) inhibitors may be a treatment for metabolic syndrome and obesity-related conditions. In mice, they found that compared with wildtype (WT) controls, animals lacking HDAC11 were lean and displayed enhanced production of metabolically active BAT. HDAC11-deficient...

Published: 5/26/2023 | Inventor(s): Timothy McKinsey, Rushita Bagchi, Bradley Ferguson, Matthew Stratton

Disease Areas Endocrine/Metabolism, Endocrine/Metabolism, Endocrine/Metabolism, Endocrine/Metabolism

Category(s): Therapeutics