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Generation of Human Motor Neurons
Lack in development of human motor neurons Human motor neuron diseases are irreversible and devastating diseases for which there are no curative treatments. Amyotrophic lateral sclerosis (ALS), spinal muscular atrophy, primary lateral sclerosis, and peripheral diabetic neuropathy are a few diseases that affect the motor neurons. Of these, ALS is the...
Published: 9/27/2023
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Inventor(s):
Holger Russ
,
Lori Sussel
,
Laura Hudish
Disease Areas
Regenerative Medicine
Category(s):
Research Tools
Inhibitory Receptor Trap (IRT): A platform for discovery and profiling of checkpoint inhibitory receptors/molecules
Inhibitory Receptor Trap (IRT): A platform for discovery and profiling of checkpoint inhibitory receptors/molecules
Published: 5/18/2023
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Inventor(s):
John Cambier
,
Bergren Crute
,
Vanessa Ott
Disease Areas
Oncology
Category(s):
Research Tools
(NIH3T3-MPRIP-NTRK1), The murine fibroblast cell line expressing the MPRIP-NTRK1 fusion gene (MPRIP-TrkA fusion protein).
(NIH3T3-MPRIP-NTRK1), The murine fibroblast cell line expressing the MPRIP-NTRK1 fusion gene (MPRIP-TrkA fusion protein).
Published: 5/9/2023
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Inventor(s):
Robert Doebele
,
Anh Le
Disease Areas
Oncology
Category(s):
Research Tools
(Ba/F3-WT NTRK1),The murine interleukin-3(IL3) dependent pro-B cell line expressing wild type human NTRK1 gene (TrkA protein).
(Ba/F3-WT NTRK1),The murine interleukin-3(IL3) dependent pro-B cell line expressing wild type human NTRK1 gene (TrkA protein).
Published: 5/9/2023
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Inventor(s):
Robert Doebele
,
Anh Le
Disease Areas
Oncology
Category(s):
Research Tools
CUTO-27 Cell Line (Colorado University Thoracic Oncology cell line, number 27), expressing an CD74-ROS1 gene fusion.
CUTO-27 Cell Line (Colorado University Thoracic Oncology cell line, number 27), expressing an CD74-ROS1 gene fusion.
Published: 5/22/2023
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Inventor(s):
Robert Doebele
,
Anh Le
Disease Areas
Oncology
Category(s):
Research Tools
CUTO-28 Cell Line (Colorado University Thoracic Oncology cell line, number 28), expressing an TPM3-ROS1 gene fusion.
CUTO-28 Cell Line (Colorado University Thoracic Oncology cell line, number 28), expressing an TPM3-ROS1 gene fusion.
Published: 5/22/2023
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Inventor(s):
Robert Doebele
,
Anh Le
Disease Areas
Oncology
Category(s):
Research Tools
Ba/F3-MPRIP-NTRK1 cell line expressing the MPRIP-NTRK1 oncogene
Ba/F3-MPRIP-NTRK1 human cell line expressing the MPRIP-NTRK1 oncogene
Published: 5/9/2023
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Inventor(s):
Robert Doebele
,
Anh Le
Disease Areas
Oncology
Category(s):
Research Tools
In vivo mouse model for testing immunotherapeutic drugs for autoimmune type 1 diabetes
Researchers developed an in vivo mouse model for testing immunotherapeutic drugs for autoimmune type-1 diabetes.
Published: 5/9/2023
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Inventor(s):
Kathryn Haskins
Disease Areas
Immunology
Category(s):
Research Tools
Recombinant adenoviruses encoding regulators of cell growth and death
The invention consists of recombinant adenoviruses that express regulators of cell growth and death (apoptosis).
Published: 5/12/2023
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Inventor(s):
James DeGregori
Disease Areas
Oncology
,
Regenerative Medicine
Category(s):
Research Tools
Human thyroid cancer cell line with the HRAS Q61R mutation
CU researchers have developed a human thyroid cancer cell line with the HRAS Q61R mutation. The cell line, called CUTC61, was derived from a 72-year-old female patient with metastatic follicular thyroid cancer (FTC) and was developed to study tumor progression and response to therapy. The CUTC61 cells can be used as in vitro cultured cell and patient-derived...
Published: 5/22/2023
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Inventor(s):
Rebecca Schweppe
,
Bryan Haugen
Disease Areas
Oncology
Category(s):
Research Tools
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