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Inhibition of the Axl Tyrosine Kinase as Biologically Targeted Cancer Therapy

A research team led by Douglas Graham has developed a fusion protein for the inhibition of Axl to be used as a therapeutic for certain cancers and thrombosis. This was accomplished by fusing the extracellular domain of Axl to a fusion partner (an Fc region of an immunoglobulin). The fusion protein then inhibits the overexpression and proliferation of...

Published: 5/30/2023 | Inventor(s): Douglas Graham, Susan Sather

Disease Areas Oncology

Category(s): Therapeutics