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CU investigators have created the first mouse model for ferroportin (Fpn) disease, also known as hemochromatosis type IV. Using the ffe mouse line, investigators have induced a missense mutation in Fpn (H32R) that affects the localization of the iron transporter and its iron export activity. These mice present with all of the features of human Fpn...

Published: 6/16/2023 | Inventor(s): Lee Niswander

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Category(s): Research Tools