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Inducible Reversible Deletion of CD11b Cells in Transgenic Rats

CU investigators have generated a transgenic rat model that allows for reversible and inducible deletion of cells that express CD11b, which includes many types of leukocytes. To do this, rats were engineered to express the diphtheria toxin receptor fused to eGFP specifically in CD11b positive cells. The research team has shown that administration of...

Published: 5/9/2023 | Inventor(s): Michael Yeager, Kelley Colvin

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Category(s): Research Tools