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Treatment of Metabolic Syndrome and Obesity with HDAC11 Inhibitors

Researchers at the University of Colorado have found that histone deacetylase 11 (HDAC11) inhibitors may be a treatment for metabolic syndrome and obesity-related conditions. In mice, they found that compared with wildtype (WT) controls, animals lacking HDAC11 were lean and displayed enhanced production of metabolically active BAT. HDAC11-deficient...

Published: 5/26/2023 | Inventor(s): Timothy McKinsey, Rushita Bagchi, Bradley Ferguson, Matthew Stratton

Disease Areas Endocrine/Metabolism, Endocrine/Metabolism, Endocrine/Metabolism, Endocrine/Metabolism

Category(s): Therapeutics