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Small Molecule Inhibitors of STAT3 for the Treatment of AML

Signal transducer and activator of transcription-3 (STAT3) is involved in multiple cancer types and inflammatory diseases. STAT3 is particularly important in leukemic stem cell proliferation and AML progression, which makes it an attractive target for therapeutic inhibition. A team of investigators at the University of Colorado led by Dr. Reigan...

Published: 11/30/2023 | Inventor(s): Philip Reigan, Donald Backos, Christopher Matheson, Steffanie Furtek

Disease Areas Oncology

Category(s): Therapeutics