Personalized Interbody Cages Accommodating Individual Endplate Architecture


­Spine interbody devices (cages) are commonly utilized in spinal fusion surgeries. In 10-30% of spinal fusion surgeries, the cage sinks into the endplates of the vertebrate weeks to months post-surgery. This complication is known as subsidence and can result in post-operative complications and follow-on surgeries. To address this issue, a research team led by Dr. Evalina Burger has developed a novel approach for manufacturing advanced interbody cages by preoperatively mapping the mechanical properties of the patient’s vertebral body endplates using conventional computed tomography (CT) scans. Gaining an understanding of the endplate’s spatial stiffness distribution and anatomy allows for the creation of a cage optimally fitted for individual endplate architecture. With this technology’s ability to personalize treatment, the inventors envision a marked reduction in postoperative subsidence development while simultaneously increasing the efficacy of spinal fusion procedures.

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Medical Devices
For Information, Contact:
Mary Tapolsky
University of Colorado
Evalina-Van Der Walt Burger
Andriy Noshchenko
Ji Ma
Vikas Patel
Christopher Kleck
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