CU researchers have developed a polyclonal antibody targeting human FIP1, which is a component of the cleavage polyadenylation factor complex with roles in mRNA processing. The antibody also recognizes dog, fish, rat and mouse FIP1 protein. Investigators have confirmed that the antibody can be used in western blotting, ELISA, flow cytometry, immunofluorescence, immunoprecipitation, and immunohistochemistry assays.
Jing J, Junutula JR, Wu C, Burden J, Peden AA, Rekeris R. FIP1/RCP binding to Gogin-97 regulates retrograde transport from recycling endosomes to Trans-Golgi Network. Molecular Biology of the Cell. 2010; 21(17):3041-53.