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Homing of Chimeric Antigen Receptor Expressing T cells to Solid Tumors

One major challenge in targeting CAR T cells to patients with solid tumors is the limited homing of CAR T cells to solid tumors. The University of Colorado research group led by Dr Michael Verneris has developed a CAR construct to target CAR-T cells to IL-8 (CXCL8) producing target tumors. This chemokine is commonly expressed by tumors (brain, lung,...

Published: 10/27/2023 | Inventor(s): Michael Verneris, Jessica Lake

Disease Areas Oncology

Category(s): Therapeutics