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Targeting Claudins to Enhance Apoptic Response of Cancer Cells
Dr.
Margaret Neville
and her research team have developed a novel peptide that targets and disrupts claudins, a family of tight junction proteins. Dr. Neville has shown that disruption of claudins initiates a cellular signaling cascade that activates the death receptor pathway causing apoptosis of epithelial cells. This disruption caused a seven-fold...
Published: 11/30/2023
|
Inventor(s):
Margaret Neville
,
Robert Hodges
,
Neal Beeman
Disease Areas
Oncology
Category(s):
Therapeutics
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