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Mouse M12.C3 B cell lines that express insulin residues linked to the mouse MHC class II molecule I-AG7

A CU scientist developed two mouse cell lines that expresses variants of the insulin B-chain residues linked to the mouse MHC class II molecules of beta and alpha I-AG7. These cell lines are derivatives of the mouse M12.C3 B cell line, which was originally derived from Balb/c mice that are negative for MHC class II molecules. The first cell line, called...

Published: 5/22/2023 | Inventor(s): Tomasz Sosinowski, John Kappler

Disease Areas Immunology, Oncology

Category(s): Research Tools