Assay for Diagnosis of Type 1A Diabetes and Other Autoimmune Diseases


A research team led by Dr. George Eisenbarth and Dr. Liping Yu has developed a novel method for the diagnosis and prediction of Type 1A diabetes in prediabetic patients. By exchanging the radioactive insulin with biotinylated and sulfo-tagged proinsulin, they were able to detect insulin autoantibodies with a plate based non-radioactive assay. This new method of plate capture for highly reproducible, non-radioactive testing for insulin autoantibodies can lead to the development of multiple assay formats to improve the prediction of Type 1A diabetes.

For Information, Contact:
Doreen Molk
University of Colorado
Liping Yu
George Eisenbarth (Deceased)
Disease Areas:
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