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A375 Melanoma Cell Line Resistant to LGD 1069, Thiazolidinediones, and the Combination

CU scientists have generated a human melanoma cell line that shows decreased proliferation in the presence of the RXR agonist LGD 1069, PPAR agonist rosiglitazone, and the combination. The cell line, called A375(DRO) cells, was created by slowly growing A375 melanoma cancer cells in the presence of each ligand or the combination. Importantly, the cell...

Published: 5/22/2023 | Inventor(s): Joshua Klopper, Bryan Haugen

Disease Areas Oncology

Category(s): Research Tools