Search Results - oncology

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Homing of Chimeric Antigen Receptor Expressing T cells to Solid Tumors

One major challenge in targeting CAR T cells to patients with solid tumors is the limited homing of CAR T cells to solid tumors. The University of Colorado research group led by Dr Michael Verneris has developed a CAR construct to target CAR-T cells to IL-8 (CXCL8) producing target tumors. This chemokine is commonly expressed by tumors (brain, lung,...

Published: 10/27/2023 | Inventor(s): Michael Verneris, Jessica Lake

Disease Areas Oncology

Category(s): Therapeutics

Automated Tracking of Fiducial Marker Clusters in X-Ray Images

The American Cancer Society estimates that 55,440 people will be diagnosed with and 44,330 will die of pancreatic cancer in 2018. An emerging treatment for this particularly lethal type of cancer involves utilizing extremely large and localized doses of radiation (stereotactic radiotherapy) to shrink the tumor and make patients candidates for surgical...

Published: 5/31/2023 | Inventor(s): Bernard Jones, Warren Campbell, Moyed Miften

Disease Areas Oncology, Radiology

Category(s): Medical Devices

Inhibitory Receptor Trap (IRT): A platform for discovery and profiling of checkpoint inhibitory receptors/molecules

Published: 5/18/2023 | Inventor(s): John Cambier, Bergren Crute, Vanessa Ott

Disease Areas Oncology

Category(s): Research Tools

(NIH3T3-MPRIP-NTRK1), The murine fibroblast cell line expressing the MPRIP-NTRK1 fusion gene (MPRIP-TrkA fusion protein).

Published: 5/9/2023 | Inventor(s): Robert Doebele, Anh Le

Disease Areas Oncology

Category(s): Research Tools

(Ba/F3-WT NTRK1),The murine interleukin-3(IL3) dependent pro-B cell line expressing wild type human NTRK1 gene (TrkA protein).