Search Results - james+degregori

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Recombinant adenoviruses encoding regulators of cell growth and death

The invention consists of recombinant adenoviruses that express regulators of cell growth and death (apoptosis).

Published: 5/12/2023 | Inventor(s): James DeGregori

Disease Areas Oncology, Regenerative Medicine

Category(s): Research Tools

Adenovirus Transducible 3T3-L1 Cells to advance genetic study of obesity

Genetic manipulation, altering native DNA or introducing foreign/exogenous DNA into cells, has proven to be an invaluable research tool to identify and study proteins integral in basic cellular function and disease but 3T3-L1 cells do not naturally lend themselves to the transfer (transduction) of genetic material. A research team led by James DeGregori...

Published: 12/1/2023 | Inventor(s): David Orlicky, James DeGregori, Jerome Schaack

Disease Areas Endocrine/Metabolism, Regenerative Medicine

Category(s): Research Tools

Genetic Manipulation of Lymphocytes to advance study of immune system

Technology developed by Dr. James DeGregori allows for efficient genetic manipulation of lymphocytes, advancing the study of the immune system in HIV/AIDS, Type I diabetes, cancer, and tissue rejection following transplant. This research group has created mice and cell lines whose lymphocytes express a truncated version of Coxsackievirus and/or...

Published: 5/4/2023 | Inventor(s): James DeGregori

Disease Areas Immunology, Regenerative Medicine

Category(s): Research Tools