Pressure-induced skin injuries are areas of damage to the skin or underlying tissue as a result of pressure or shear. Pressure-induced skin and soft tissue injuries are considered never events by CMS. There has been an unmet need for devices for the prevention of pressure ulcers. Recent developments in polymer-based nanofabrication shows promise in addressing these challenges. A team led by Dr. Ken Liechty has created a technology for the prevention of pressure ulcers using silk fibroin (SF) nanofibers composed of a cream. Silk fibers increase the elasticity and tensile strength of skin and has been demonstrated to prevent stage 4 pressure ulcers in mouse models.