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Antimicrobial Peptides to Treat Gram-negative infections
The growing emergence of pathogenic bacteria with clinical significant resistance to conventional antibiotics is a major public health concern. There has been a revival of polymyxins which have serious issues of nephrotoxicity/ neurotoxicity as antibiotics of last resort. Resistance to polymyxins means that no antibiotics are available for the treatment...
Published: 5/7/2023   |   Inventor(s): Robert Hodges, Colin Mant, Lajos Gera, Ziqing Jiang
Disease Areas  
Category(s): Therapeutics
Novel Compounds Show Promise in Treating Variety of Cancers
A group of researchers led by Lajos Gera and Robert Hodges has developed two sets of compounds: flurbiprofen analogs and silylalkyloxyaryl amino acid analog compounds that have proven to be effective against a wide variety of cancer cell lines. Both were screened using the NCI-60 cell lines, a panel of 60 diverse human cancer cell lines used by National...
Published: 5/7/2023   |   Inventor(s): Lajos Gera, Robert Hodges, Peter Hegyes, Daniel Muruve
Disease Areas Oncology
Category(s): Therapeutics
Novel Compounds Show Promise in Treating Variety of Cancers
A group of researchers led by Lajos Gera and Robert Hodges has developed two sets of compounds: flurbiprofen analogs and silylalkyloxyaryl amino acid analog compounds that have proven to be effective against a wide variety of cancer cell lines. Both were screened using the NCI-60 cell lines, a panel of 60 diverse human cancer cell lines used by National...
Published: 5/21/2023   |   Inventor(s): Lajos Gera, Daniel Chuen-Fong Chan, Robert Hodges, Paul Bunn
Disease Areas Oncology
Category(s): Therapeutics
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