Search Results - liudmila+kulik

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A Novel Non-Immunogenic Mouse Monoclonal Antibody that Recognizes Mouse CR2 and Inhibits its Function in Chronic Disease Models

CU investigators have generated a novel antibody that recognizes Compliment Receptor 2 (CR2). This antibody was raised in CR2 deficient mice and is non-immunogenic when administered in vivo. Importantly, the antibody blocks the function of mouse CR2 and can be used to study how CR2 receptor blockage modifies disease activity in proof-of-concept mouse...

Published: 5/22/2023 | Inventor(s): V. Michael Holers, Liudmila Kulik

Disease Areas Immunology

Category(s): Research Tools

Composition and description of novel anti-C3d monoclonal antibodies used for non-invasive detection of complement activation fragments in vivo

Systemic lupus erythematosus (SLE) is an autoimmune disease which can affect different organs throughout the body and is battled by nearly 4 million Americans in the United States. Up to 50% of patients with SLE develop renal abnormalities during the disease’s progression. Not only are biopsies invasive and carry their own complications, but the...

Published: 12/1/2023 | Inventor(s): V. Michael Holers, Joshua Thurman, Liudmila Kulik

Disease Areas Immunology

Category(s): Diagnostics