Search Results - luisa+mestroni

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Treatment For Filamin C-Related Cardiomyopathies

Filamin C (FLNC) mutations have been identified as a genetic cause of dilated cardiomyopathy (DCM) with an arrhythmogenic phenotype and an increased risk for sudden cardiac death due to ventricular arrhythmias. Many of these patients also develop heart failure, requiring heart transplant. Unfortunately, there are currently no specific treatments...

Published: 5/10/2023 | Inventor(s): Suet Nee Chen, Luisa Mestroni, Joseph Wu, Matthew R.G. Taylor, Ying Wooi Wan, Chi Keung Lam

Disease Areas Cardiology, Regenerative Medicine

Category(s): Therapeutics

NanoCardioLab: Exploring the Heart at the Micro-and Nanoscale

The inventors’ team, led by Dr. Luisa Mestroni of CU, has discovered that changes observed in neurons when exposed to carbon nanotubes (CNTs) could be reproduced in cardiac myocytes. Their work has shown increased viability and proliferation of cardiac myocytes (neonatal rat ventricular myocytes, NRVM) when interacting with CNTs, as well as changes...

Published: 5/24/2023 | Inventor(s): Luisa Mestroni, Laura Ballerini, Carlin Long, John Caldwell, Valentia Martinelli, Giada Cellot, Francesca Toma, Lorenza Zentilin, Maurizio Prato

Disease Areas Cardiology, Regenerative Medicine

Category(s): Therapeutics

Carbon Nanotube-Functionalized Reverse Thermal Gel for Cardiac Tissue Engineering

Approximately 422.7 million heart diseases cases are diagnosed annually across the globe. The dysfunction and death of specialized muscle cells, cardiomyocytes, cause many of these heart failures to occur. The adult heart has scarce capability to regenerate these cells after injury and access to heart transplants is limited. Regenerative medicine has...

Published: 8/29/2022 | Inventor(s): Brisa Pena Castellanos, Daewon Park, Luisa Mestroni, Susanna Bosi

Disease Areas Cardiology

Category(s): Therapeutics