Search Results - ophthalmology

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Intraocular Device for Correction of Aphakia and Restoration of Accommodation

Background on CU3886H Over 2 million cataract surgeries are performed each year in the U.S. Currently, there are 3 million patients with glaucoma in the U.S. Everyone over the age of 50 will eventually lose their accommodative ability, requiring the use of reading glasses in most individuals. There is no singular device that addresses all three...

Published: 5/13/2023 | Inventor(s): Jeffrey Olson, Michael Erlanger

Disease Areas Ophthalmology

Category(s): Medical Devices

Hitch Injector for Ophthalmic Surgery

Background on CU3336H For even incredibly skilled surgeons, suturing inside an eye is technically challenging due to space constraints. A skilled surgeon can take twenty times longer to suture inside the eye compared to conventional suturing. Millions of eye surgeries are done each year that require the securement of an intraocular object. The...

Published: 5/22/2023 | Inventor(s): Jeffrey Olson

Disease Areas Ophthalmology

Category(s): Medical Devices

Implanted glaucoma drainage device regulator

Background on CU3038H: About 3 million people in the United States are affected by glaucoma which may lead to blindness. That number is expected to increase to more than 4 million by 2030. To decrease the intraocular high pressure characterizing glaucoma, current treatments include topical medications, laser treatments or surgery. For the most advanced...

Published: 5/22/2023 | Inventor(s): Jeffrey Olson, Ramanath Bhandari

Disease Areas Ophthalmology

Category(s): Medical Devices

Vitreous Drug Delivery And Filter Device

Dr. Jeff Olson with researchers in the Department of Ophthalmology have developed an implantable device placed surgically into the vitreous cavity. The porous material (such as hydroxyapatite, ceramics, etc) can be preloaded with drug, such as those used to treat macular degeneration, glaucoma, diabetic retinopathy, etc. The drug is slowly released...

Published: 5/22/2023 | Inventor(s): Jeffrey Olson

Disease Areas Ophthalmology

Category(s): Medical Devices

Monoclonal Antibody to ab-Crystallin Chaperone Protein ABCP

CU investigators have generated a monoclonal antibody that recognizes the protein ABCP, which is the core domain of molecular chaperone protein alpha,beta-crystallin. The antibody isotype is IgG2a1 and can be used to detect ABCP as well as a peptide region within ab-crystallin where ABCP binds. The research team has demonstrated that the antibody is...

Published: 5/22/2023 | Inventor(s): Ram Nagaraj, Rooban Nahomi

Disease Areas Ophthalmology

Category(s): Research Tools

A Novel Inhibitor for Advanced Glycation and Protein Crosslinking

Dr. Ram Nagaraj and a team of researchers have developed a novel molecule, Carboxitin that significantly reduces crosslinking and Advanced Glycation Endproducts (AGEs) formation in eye tissues to reduce lens stiffness. This compound may have the potential to treat diabetic eye complications, cataracts, presbyopia, and age-related macular degeneration....

Published: 5/22/2023 | Inventor(s): Ram Nagaraj, Mikhal Linetsky, Rooban Nahomi, Stefan Rakete

Disease Areas Ophthalmology

Category(s): Therapeutics