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Serum Immunoglobulin G1 (IgG1) and G3 (IgG3) subclasses as biomarkers for multiple sclerosis

Multiple sclerosis (MS) is a chronic inflammatory disease of the CNS with demyelination and neuronal damage and is the most common cause of neurological disability in young adults. In 2021, roughly 784,000 Americans were living with MS. A characteristic feature of MS is the increased intrathecal synthesis of IgG, and the presence of oligoclonal...

Published: 6/7/2023 | Inventor(s): Xiaoli Yu, Michael Graner, Wenbo Zhou, Timothy Vollmer, Enrique Alvarez

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Category(s): Diagnostics