Search Results - patrick+mcgrath

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RNA Cocktail to Restore Function in Aged Cells

Aged Cells or Tissues used for Autologous Therapies have Poor Efficacy Autologous cells used for tissue transplant therapies or adoptive cell therapies become poorly functional because of aging caused by either (1) patient age (elderly patient) or (2) induced aging via ex-vivo expansion protocols. Restoring function in aged cells is critical to improve...

Published: 9/27/2023 | Inventor(s): Igor Kogut, Ganna Bilousova, Patrick McGrath, Nicole Diette

Disease Areas Regenerative Medicine

Category(s): Therapeutics

High Efficiency Generation of Integration-free iPSCs for the Clinic

iPSC Reprogramming Challenges Induced pluripotent stem cells (iPSCs) are a type of pluripotent stem cell generated directly from adult cells that can propagate indefinitely to give rise to every other cell type in the body. iPSCs are a valuable tool to study human development and disease. They are also useful for drug discovery and the development of...

Published: 10/6/2023 | Inventor(s): Ganna Bilousova, Igor Kogut, Dennis Roop, Patrick McGrath

Disease Areas Regenerative Medicine

Category(s): Therapeutics