Search Results - hematology

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AMPD2 Inhibitors for Treatment/Prevention of Obesity, Diabetes, Metabolic Syndrome, Fatty Liver and Hypertension

Metabolic syndrome combines a variety of medical disorders including obesity, type 1 diabetes, insulin resistance, and refractory hypertension, all of which increase the risk of developing cardiovascular disease. A research group led by Dr. Richard Johnson has identified the use of a specific variant of adenosine monophosphate deaminase 2 (AMPD2) as...

Published: 11/30/2023 | Inventor(s): Richard Johnson, Gabriela Garcia, Christopher Rivard, Miguel Lanaspa-Garcia

Disease Areas Endocrine/Metabolism, Endocrine/Metabolism, Endocrine/Metabolism, Endocrine/Metabolism, Hematology

Category(s): Therapeutics

3-D Reconstruction of Coronary Artery Structures

Researchers led by John Carroll and S. James Chen developed a novel method for three-dimensional reconstruction of vessels while also providing improved quantitative coronary analysis (QCA) techniques utilizing such 3-D reconstructions. This method of reconstruction solves the problems associated with other 3-D imaging techniques by providing a more...

Published: 11/14/2023 | Inventor(s): John Carroll, James Chen

Disease Areas Hematology

Category(s): Software

Cystathionine for Treatment of Liver and Kidney Injury, Cardiovascular Protection & Chemotherapy Potentiation

Researchers have discovered that cystathionine reduces the development of toxin-induced liver and/or kidney disease and is also capable of blocking tunicamycin-mediated tissue injury and apoptosis. Findings suggest that cystathionine may be a new treatment option in many disease states where cell death is triggered by stress to the endoplasmic reticulum...

Published: 5/22/2023 | Inventor(s): Kenneth MacLean, Richard Austin

Disease Areas Hematology, Regenerative Medicine

Category(s): Therapeutics