Search Results - maki+nakayama

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Genetically Engineered Treg Cell Therapy for Immune Disorders

Adoptive Cell Therapies for Chronic Inflammatory and Autoimmune Disorders Chronic inflammatory and autoimmune disorders affect over 3% of the US population with no treatment options available that sustainably reverses symptoms or cures patients. Adoptive Treg cell therapies are promising treatment options due to their ability to persistently induce...

Published: 10/23/2023 | Inventor(s): Mayumi Fujita, Douglas Osborne, Maki Nakayama

Disease Areas Regenerative Medicine

Category(s): Therapeutics

Antigen Presenting Cell Line Expressing HLA-DQ8

CU researchers developed a human myelogenic leukemia cell line that expresses a human leukocyte antigen HLA-DQ8 (DQA1*0301 and DQB1*0302). The cell line is a derivative of K562, which was obtained from the bone marrow of a 53-year-old female with chronic myelogenous leukemia. Here, the K562 cell line was engineered using a replication-incompetent retrovirus...

Published: 5/22/2023 | Inventor(s): Maki Nakayama

Disease Areas Immunology

Category(s): Research Tools