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CD8 Targeting CAR-T Cells for Autoimmune Disorders
Necessity of CAR-T Targeting Autoimmunity There is a need for more antigen targets for CAR-based therapies treating autoimmune disorders, solid organ transplant rejection, and T-cell leukemia. Pathogenic CD8 T-cells are one of the drivers for the listed indications and presents a promising target for CAR-based therapies. CD8 Targeting CAR-T Cell Therapy Dr....
Published: 10/23/2023   |   Inventor(s): Terry Fry
Disease Areas Regenerative Medicine
Category(s): Therapeutics
Novel Costimulatory Platform for CAR-Based Adoptive Cell Therapies
Ineffective targeting of current CAR T Chimeric antigen receptor (CAR) T cell therapy is a powerful treatment tool for multiple types of malignancies. There are six FDA approved CAR T therapies that have demonstrated efficacy in patients who are refractory to standard chemotherapy, with many patients entering remission after treatment. However, most...
Published: 10/23/2023   |   Inventor(s): Mark Kohler, Terry Fry, Catherine Danis, Lillie Leach
Disease Areas Regenerative Medicine
Category(s): Therapeutics
Novel Costimulatory Platform for CAR-Based Adoptive Cell Therapies
Ineffective targeting of current CAR T Chimeric antigen receptor (CAR) T cell therapy is a powerful treatment tool for multiple types of malignancies. There are six FDA approved CAR T therapies that have demonstrated efficacy in patients who are refractory to standard chemotherapy, with many patients entering remission after treatment. However, most...
Published: 10/23/2023   |   Inventor(s): Mark Kohler, Catherine Danis, Terry Fry, Lillie Leach
Disease Areas Regenerative Medicine
Category(s): Therapeutics
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